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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK15
All Species:
8.79
Human Site:
S442
Identified Species:
19.33
UniProt:
Q8TD08
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TD08
NP_620590.2
544
59832
S442
E
A
P
P
L
T
L
S
L
V
K
P
S
G
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539201
559
60934
S453
A
A
A
P
S
A
P
S
W
V
E
P
S
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80Y86
549
60660
S444
G
Q
P
P
S
A
P
S
G
V
K
T
Q
V
R
Rat
Rattus norvegicus
Q9Z2A6
547
60705
S442
G
E
P
P
S
A
P
S
G
V
K
T
H
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423954
600
66936
S464
I
H
N
P
I
T
R
S
A
A
Q
T
G
N
A
Frog
Xenopus laevis
P26696
361
41238
F282
K
V
P
W
N
R
L
F
P
N
A
D
P
K
A
Zebra Danio
Brachydanio rerio
NP_001018581
524
58806
P439
F
S
L
T
L
A
Q
P
L
N
N
P
L
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392445
747
85295
K541
D
K
L
R
R
N
N
K
Q
I
R
T
T
N
R
Nematode Worm
Caenorhab. elegans
Q11179
470
54020
T391
T
A
R
S
L
Q
R
T
T
S
M
D
K
N
N
Sea Urchin
Strong. purpuratus
XP_001203135
583
64666
A464
Q
N
S
V
E
N
I
A
A
G
Q
Y
N
G
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P14681
368
42674
L289
L
N
P
D
M
I
D
L
L
D
K
M
L
Q
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
71.5
N.A.
69.2
68.7
N.A.
N.A.
45.3
28.6
48.3
N.A.
N.A.
34.6
42.6
44.9
Protein Similarity:
100
N.A.
N.A.
77.8
N.A.
75.5
75.1
N.A.
N.A.
60
42
64.8
N.A.
N.A.
50.5
61.2
62.6
P-Site Identity:
100
N.A.
N.A.
46.6
N.A.
40
40
N.A.
N.A.
20
13.3
26.6
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
N.A.
60
N.A.
40
40
N.A.
N.A.
33.3
20
33.3
N.A.
N.A.
33.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
10
0
0
37
0
10
19
10
10
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
10
0
0
10
0
0
10
0
19
0
0
0
% D
% Glu:
10
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% F
% Gly:
19
0
0
0
0
0
0
0
19
10
0
0
10
28
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
10
10
10
0
0
10
0
0
0
10
0
% I
% Lys:
10
10
0
0
0
0
0
10
0
0
37
0
10
10
10
% K
% Leu:
10
0
19
0
28
0
19
10
28
0
0
0
19
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
19
10
0
10
19
10
0
0
19
10
0
10
28
19
% N
% Pro:
0
0
46
46
0
0
28
10
10
0
0
28
10
0
0
% P
% Gln:
10
10
0
0
0
10
10
0
10
0
19
0
10
10
0
% Q
% Arg:
0
0
10
10
10
10
19
0
0
0
10
0
0
0
46
% R
% Ser:
0
10
10
10
28
0
0
46
0
10
0
0
19
0
0
% S
% Thr:
10
0
0
10
0
19
0
10
10
0
0
37
10
0
0
% T
% Val:
0
10
0
10
0
0
0
0
0
37
0
0
0
19
0
% V
% Trp:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _